At what point in gestation does the trilaminar endometrium develop?

The trilaminar endometrium, which consists of three layers—the basal layer, the functional layer, and the spongy layer—is formed during the late proliferative phase of the menstrual cycle. This phase takes place just before ovulation within the first trimester of pregnancy.

The late proliferative phase is characterized by estrogen-driven proliferation of the endometrial tissue in preparation for potential implantation of an embryo. During this period, the endometrium undergoes significant changes to support a fertilized ovum, evolving from a simple two-layer structure to the more complex trilaminar configuration.

In gestation, recognizing the development of the trilaminar endometrium is key as it signifies the endometrial readiness for implantation and sustenance of a developing embryo. Understanding this phase is critical for sonographers and healthcare professionals involved in prenatal care, as it lays the foundation for subsequent stages of pregnancy and influences early placental development.